A randomized phase 3 trial of zanubrutinib vs ibrutinib in symptomatic Waldenström macroglobulinemia: the ASPEN study.

Constantine S. Tam; Stephen Opat; Shirley D'Sa; Wojciech Jurczak; Hui Peng Lee; Gavin Cull; Gavin Cull; Roger G. Owen; Paula Marlton; Paula Marlton; Björn E. Wahlin; Ramón Garcia Sanz; Helen McCarthy; Stephen Mulligan; Alessandra Tedeschi; Jorge J. Castillo; Jaroslaw Czyz; Carlos Fernández de Larrea; David Belada; Edward Libby; Jeffrey V. Matous; Marina Motta; Tanya Siddiqi; Monica Tani; Marek Trneny; Monique C. Minnema; Christian Buske; Veronique Leblond; Judith Trotman; Judith Trotman; Wai Y. Chan; Jingjing Schneider; Sunhee Ro; Aileen Cohen; Jane Huang; Meletios Dimopoulos

doi:10.1182/BLOOD.2020006844

A randomized phase 3 trial of zanubrutinib vs ibrutinib in symptomatic Waldenström macroglobulinemia: the ASPEN study.

Constantine S. Tam
, Stephen Opat
, Shirley D'Sa
, Wojciech Jurczak
, Hui Peng Lee
, Gavin Cull
, Gavin Cull
, Roger G. Owen
, Paula Marlton
, Paula Marlton
, Björn E. Wahlin
, Ramón Garcia Sanz
, Helen McCarthy
, Stephen Mulligan
, Alessandra Tedeschi
, Jorge J. Castillo
, Jaroslaw Czyz
, Carlos Fernández de Larrea
, David Belada
, Edward Libby

Jeffrey V. Matous, Marina Motta, Tanya Siddiqi, Monica Tani, Marek Trneny, Monique C. Minnema, Christian Buske, Veronique Leblond, Judith Trotman, Judith Trotman, Wai Y. Chan, Jingjing Schneider, Sunhee Ro, Aileen Cohen, Jane Huang, Meletios Dimopoulos

Peter MacCallum Cancer Centre, Melbourne, VIC, Australia.
Monash University, Clayton campus
University College Hospital
Maria Sklodowska-Curie National Institute of Oncology, Krakow, Poland.
Flinders Medical Centre
University of Western Australia
Sir Charles Gairdner Hospital
St James's University Hospital
University of Queensland
Princess Alexandra Hospital
Karolinska University Hospital
Hospital Universitario de Salamanca, Salamanca, Spain
Christchurch Hospital
Royal North Shore Hospital
ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy.
Harvard University
Nicolaus Copernicus University in Toruń
University of Barcelona
Charles University in Prague
Seattle Cancer Care Alliance
Colorado Blood Cancer Institute, Denver, CO
ASST Spedali Civili di Brescia, Lombardia, Italy.
City of Hope National Medical Center
Academy for Urban School Leadership
First Faculty of Medicine, Charles University in Prague
Utrecht University
Comprehensive Cancer Center Ulm-Universitätsklinikum Ulm, Ulm, Germany.
University of Paris
University of Sydney
Concord Repatriation General Hospital
BeiGene USA, Inc, San Mateo, CA; and.
National and Kapodistrian University of Athens

Research output: Contribution to journal › Article › peer-review

Original language	American English
Journal	Blood
Volume	136
Issue number	18
DOIs	https://doi.org/10.1182/BLOOD.2020006844
State	Published - Oct 29 2020
Externally published	Yes

Disciplines

Medicine and Health Sciences
Gastroenterology
Internal Medicine

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10.1182/BLOOD.2020006844License: Unspecified

Cite this

Tam, C. S., Opat, S., D'Sa, S., Jurczak, W., Lee, H. P., Cull, G., Cull, G., Owen, R. G., Marlton, P., Marlton, P., Wahlin, B. E., Sanz, R. G., McCarthy, H., Mulligan, S., Tedeschi, A., Castillo, J. J., Czyz, J., de Larrea, C. F., Belada, D., ... Dimopoulos, M. (2020). A randomized phase 3 trial of zanubrutinib vs ibrutinib in symptomatic Waldenström macroglobulinemia: the ASPEN study. Blood, 136(18). https://doi.org/10.1182/BLOOD.2020006844

Tam, CS, Opat, S, D'Sa, S, Jurczak, W, Lee, HP, Cull, G, Cull, G, Owen, RG, Marlton, P, Marlton, P, Wahlin, BE, Sanz, RG, McCarthy, H, Mulligan, S, Tedeschi, A, Castillo, JJ, Czyz, J, de Larrea, CF, Belada, D, Libby, E, Matous, JV, Motta, M, Siddiqi, T, Tani, M, Trneny, M, Minnema, MC, Buske, C, Leblond, V, Trotman, J, Trotman, J, Chan, WY, Schneider, J, Ro, S, Cohen, A, Huang, J & Dimopoulos, M 2020, 'A randomized phase 3 trial of zanubrutinib vs ibrutinib in symptomatic Waldenström macroglobulinemia: the ASPEN study.', Blood, vol. 136, no. 18. https://doi.org/10.1182/BLOOD.2020006844

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title = "A randomized phase 3 trial of zanubrutinib vs ibrutinib in symptomatic Waldenstr{\"o}m macroglobulinemia: the ASPEN study.",

author = "Tam, \{Constantine S.\} and Stephen Opat and Shirley D'Sa and Wojciech Jurczak and Lee, \{Hui Peng\} and Gavin Cull and Gavin Cull and Owen, \{Roger G.\} and Paula Marlton and Paula Marlton and Wahlin, \{Bj{\"o}rn E.\} and Sanz, \{Ram{\'o}n Garcia\} and Helen McCarthy and Stephen Mulligan and Alessandra Tedeschi and Castillo, \{Jorge J.\} and Jaroslaw Czyz and \{de Larrea\}, \{Carlos Fern{\'a}ndez\} and David Belada and Edward Libby and Matous, \{Jeffrey V.\} and Marina Motta and Tanya Siddiqi and Monica Tani and Marek Trneny and Minnema, \{Monique C.\} and Christian Buske and Veronique Leblond and Judith Trotman and Judith Trotman and Chan, \{Wai Y.\} and Jingjing Schneider and Sunhee Ro and Aileen Cohen and Jane Huang and Meletios Dimopoulos",

note = "Constantine S. Tam, Stephen Opat, Shirley D'Sa, Wojciech Jurczak, Hui-Peng Lee, Gavin Cull, Roger G. Owen, Paula Marlton, Bj{\"o}rn E. Wahlin, Ram{\'o}n Garcia Sanz, Helen McCarthy, Stephen Mulligan, Alessandra Tedeschi, Jorge J. Castillo, Jaroslaw Czyz, Carlos Fern{\'a}ndez de Larrea, David Belada, Edward Libby, Jeffrey V.",

year = "2020",

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day = "29",

doi = "10.1182/BLOOD.2020006844",

language = "American English",

volume = "136",

journal = "Blood",

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T1 - A randomized phase 3 trial of zanubrutinib vs ibrutinib in symptomatic Waldenström macroglobulinemia: the ASPEN study.

AU - Tam, Constantine S.

AU - Opat, Stephen

AU - D'Sa, Shirley

AU - Jurczak, Wojciech

AU - Lee, Hui Peng

AU - Cull, Gavin

AU - Owen, Roger G.

AU - Marlton, Paula

AU - Wahlin, Björn E.

AU - Sanz, Ramón Garcia

AU - McCarthy, Helen

AU - Mulligan, Stephen

AU - Tedeschi, Alessandra

AU - Castillo, Jorge J.

AU - Czyz, Jaroslaw

AU - de Larrea, Carlos Fernández

AU - Belada, David

AU - Libby, Edward

AU - Matous, Jeffrey V.

AU - Motta, Marina

AU - Siddiqi, Tanya

AU - Tani, Monica

AU - Trneny, Marek

AU - Minnema, Monique C.

AU - Buske, Christian

AU - Leblond, Veronique

AU - Trotman, Judith

AU - Chan, Wai Y.

AU - Schneider, Jingjing

AU - Ro, Sunhee

AU - Cohen, Aileen

AU - Huang, Jane

AU - Dimopoulos, Meletios

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PY - 2020/10/29

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UR - https://ashpublications.org/blood/article/136/18/2038/461625/A-randomized-phase-3-trial-of-zanubrutinib-vs

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DO - 10.1182/BLOOD.2020006844

M3 - Article

VL - 136

JO - Blood

JF - Blood

IS - 18

ER -

A randomized phase 3 trial of zanubrutinib vs ibrutinib in symptomatic Waldenström macroglobulinemia: the ASPEN study.

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