Abstract 4159: Characterization of the T-cell receptor (TCR) repertoire in extensive disease small cell lung cancer (ED SCLC)

Maen Hussein; Sharon Wilks; Marc Monte; Donald A. Richards; Jerome H. Goldschmidt; David Waterhouse; Lisu Wang; Saumya Pant; Erik Yusko; Ryan O. Emerson; Darin M. Taverna; Kaushal Desai; Spyro Mousses; Zhenhao Qi; Jason D. Hipp; Harlan Robins; Kimary Kulig; Cory Batenchuk

doi:10.1158/1538-7445.AM2016-4159

Abstract 4159: Characterization of the T-cell receptor (TCR) repertoire in extensive disease small cell lung cancer (ED SCLC)

Maen Hussein
, Sharon Wilks
, Marc Monte
, Donald A. Richards
, Jerome H. Goldschmidt
, David Waterhouse
, Lisu Wang
, Saumya Pant
, Erik Yusko
, Ryan O. Emerson
, Darin M. Taverna
, Kaushal Desai
, Spyro Mousses
, Zhenhao Qi
, Jason D. Hipp
, Harlan Robins
, Kimary Kulig
, Cory Batenchuk

Florida Cancer Specialists, Lady Lake, FL;
Cancer Care Center of South Texas, TX;
Clopton Clinic of Jonesboro, Inc, AR;
Texas Oncology
Blue Ridge Cancer Care, VA;
Oncology Hematology Care, OH;
Bristol-Myers Squibb
Adaptive Biotechnologies, WA;
Systems Imagination, Inc, AZ.

Research output: Contribution to journal › Article › peer-review

Original language	American English
Journal	Cancer Research
Volume	76
DOIs	https://doi.org/10.1158/1538-7445.AM2016-4159
State	Published - Jul 15 2016
Externally published	Yes

Disciplines

Immunology and Infectious Disease
Biology

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Hussein, M., Wilks, S., Monte, M., Richards, D. A., Goldschmidt, J. H., Waterhouse, D., Wang, L., Pant, S., Yusko, E., Emerson, R. O., Taverna, D. M., Desai, K., Mousses, S., Qi, Z., Hipp, J. D., Robins, H., Kulig, K., & Batenchuk, C. (2016). Abstract 4159: Characterization of the T-cell receptor (TCR) repertoire in extensive disease small cell lung cancer (ED SCLC). Cancer Research, 76. https://doi.org/10.1158/1538-7445.AM2016-4159

Hussein, M, Wilks, S, Monte, M, Richards, DA, Goldschmidt, JH, Waterhouse, D, Wang, L, Pant, S, Yusko, E, Emerson, RO, Taverna, DM, Desai, K, Mousses, S, Qi, Z, Hipp, JD, Robins, H, Kulig, K & Batenchuk, C 2016, 'Abstract 4159: Characterization of the T-cell receptor (TCR) repertoire in extensive disease small cell lung cancer (ED SCLC)', Cancer Research, vol. 76. https://doi.org/10.1158/1538-7445.AM2016-4159

@article{7e255663eb6745c8ad10fc1e6864cc2f,

title = "Abstract 4159: Characterization of the T-cell receptor (TCR) repertoire in extensive disease small cell lung cancer (ED SCLC)",

author = "Maen Hussein and Sharon Wilks and Marc Monte and Richards, \{Donald A.\} and Goldschmidt, \{Jerome H.\} and David Waterhouse and Lisu Wang and Saumya Pant and Erik Yusko and Emerson, \{Ryan O.\} and Taverna, \{Darin M.\} and Kaushal Desai and Spyro Mousses and Zhenhao Qi and Hipp, \{Jason D.\} and Harlan Robins and Kimary Kulig and Cory Batenchuk",

note = "Proceedings: AACR 107th Annual Meeting 2016; April 16-20, 2016; New Orleans, LA Background: The current study explores T-cell (TC) clonality and molecular factors associated with this metric. Tumors employ multiple mechanisms to evade antitumor immune responses. One process involves TC inhibition via upregulation of immune checkpoint (IC) ligands in the tumor microenvironment (TME).",

year = "2016",

month = jul,

day = "15",

doi = "10.1158/1538-7445.AM2016-4159",

language = "American English",

volume = "76",

journal = "Cancer Research",

issn = "1538-7445",

publisher = "American Association for Cancer Research",

}

TY - JOUR

T1 - Abstract 4159: Characterization of the T-cell receptor (TCR) repertoire in extensive disease small cell lung cancer (ED SCLC)

AU - Hussein, Maen

AU - Wilks, Sharon

AU - Monte, Marc

AU - Richards, Donald A.

AU - Goldschmidt, Jerome H.

AU - Waterhouse, David

AU - Wang, Lisu

AU - Pant, Saumya

AU - Yusko, Erik

AU - Emerson, Ryan O.

AU - Taverna, Darin M.

AU - Desai, Kaushal

AU - Mousses, Spyro

AU - Qi, Zhenhao

AU - Hipp, Jason D.

AU - Robins, Harlan

AU - Kulig, Kimary

AU - Batenchuk, Cory

N1 - Proceedings: AACR 107th Annual Meeting 2016; April 16-20, 2016; New Orleans, LA Background: The current study explores T-cell (TC) clonality and molecular factors associated with this metric. Tumors employ multiple mechanisms to evade antitumor immune responses. One process involves TC inhibition via upregulation of immune checkpoint (IC) ligands in the tumor microenvironment (TME).

PY - 2016/7/15

Y1 - 2016/7/15

UR - https://cancerres.aacrjournals.org/content/76/14_Supplement/4159

U2 - 10.1158/1538-7445.AM2016-4159

DO - 10.1158/1538-7445.AM2016-4159

M3 - Article

SN - 1538-7445

VL - 76

JO - Cancer Research

JF - Cancer Research

ER -

Abstract 4159: Characterization of the T-cell receptor (TCR) repertoire in extensive disease small cell lung cancer (ED SCLC)

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