Acute Myeloid Leukemia Complicated by Hyperleukocytosis and Leukostasis in the Emergency Department

Ryan T Ngo; Amanda Webb; Anthony Furiato

Acute Myeloid Leukemia Complicated by Hyperleukocytosis and Leukostasis in the Emergency Department

Ryan T Ngo
, Amanda Webb
, Anthony Furiato

HCA Florida Brandon Hospital

HCA Healthcare

Research output: Contribution to journal › Article › peer-review

Abstract

Acute myeloid leukemia (AML) and other hematologic malignancies can be complicated by hyperleukocytosis, which leads to an increased risk for other severe complications such as tumor lysis syndrome, disseminated intravascular coagulation (DIC), and leukostasis. In this report, we present a case of a 65-year-old female with newly diagnosed AML complicated by leukostasis. We briefly review the clinical significance as well as initial diagnostic and therapeutic considerations pertaining to hyperleukocytosis and its associated complications.

Original language	American English
Journal	Emergency Medicine
State	Published - Jun 2 2021

Keywords

acute myeloid leukemia
hyperleukocytosis
leukostasis
hematologic malignancies
blast crisis

Disciplines

Emergency Medicine
Hematology
Hemic and Lymphatic Diseases
Neoplasms
Oncology

Access to Document

https://doi.org/10.7759/cureus.15392

Cite this

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title = "Acute Myeloid Leukemia Complicated by Hyperleukocytosis and Leukostasis in the Emergency Department",

abstract = " Acute myeloid leukemia (AML) and other hematologic malignancies can be complicated by hyperleukocytosis, which leads to an increased risk for other severe complications such as tumor lysis syndrome, disseminated intravascular coagulation (DIC), and leukostasis. In this report, we present a case of a 65-year-old female with newly diagnosed AML complicated by leukostasis. We briefly review the clinical significance as well as initial diagnostic and therapeutic considerations pertaining to hyperleukocytosis and its associated complications.",

keywords = "acute myeloid leukemia, hyperleukocytosis, leukostasis, hematologic malignancies, blast crisis",

author = "Ngo, \{Ryan T\} and Amanda Webb and Anthony Furiato",

note = "Ngo R T, Webb Mcadams AL, Furiato A. Acute Myeloid Leukemia Complicated by Hyperleukocytosis and Leukostasis in the Emergency Department. Cureus. 2021;13(6):e15392. https://doi/org/10.7759/cureus.15392",

year = "2021",

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language = "American English",

journal = "Emergency Medicine",

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TY - JOUR

T1 - Acute Myeloid Leukemia Complicated by Hyperleukocytosis and Leukostasis in the Emergency Department

AU - Ngo, Ryan T

AU - Webb, Amanda

AU - Furiato, Anthony

N1 - Ngo R T, Webb Mcadams AL, Furiato A. Acute Myeloid Leukemia Complicated by Hyperleukocytosis and Leukostasis in the Emergency Department. Cureus. 2021;13(6):e15392. https://doi/org/10.7759/cureus.15392

PY - 2021/6/2

Y1 - 2021/6/2

N2 - Acute myeloid leukemia (AML) and other hematologic malignancies can be complicated by hyperleukocytosis, which leads to an increased risk for other severe complications such as tumor lysis syndrome, disseminated intravascular coagulation (DIC), and leukostasis. In this report, we present a case of a 65-year-old female with newly diagnosed AML complicated by leukostasis. We briefly review the clinical significance as well as initial diagnostic and therapeutic considerations pertaining to hyperleukocytosis and its associated complications.

AB - Acute myeloid leukemia (AML) and other hematologic malignancies can be complicated by hyperleukocytosis, which leads to an increased risk for other severe complications such as tumor lysis syndrome, disseminated intravascular coagulation (DIC), and leukostasis. In this report, we present a case of a 65-year-old female with newly diagnosed AML complicated by leukostasis. We briefly review the clinical significance as well as initial diagnostic and therapeutic considerations pertaining to hyperleukocytosis and its associated complications.

KW - acute myeloid leukemia

KW - hyperleukocytosis

KW - leukostasis

KW - hematologic malignancies

KW - blast crisis

UR - https://scholarlycommons.hcahealthcare.com/emergency/135

UR - https://doi.org/10.7759/cureus.15392

M3 - Article

JO - Emergency Medicine

JF - Emergency Medicine

ER -

Acute Myeloid Leukemia Complicated by Hyperleukocytosis and Leukostasis in the Emergency Department

Abstract

Keywords

Disciplines

Access to Document

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