Adrenal Crisis Secondary to Influenza and Tetanus Vaccination in an Adult Without Known Adrenal Insufficiency: A Case of Autoimmune Adrenalitis

Shiwani Kamath; Jessica Khabra; Parth R Desai; Johnathan Frunzi

Adrenal Crisis Secondary to Influenza and Tetanus Vaccination in an Adult Without Known Adrenal Insufficiency: A Case of Autoimmune Adrenalitis

Shiwani Kamath
, Jessica Khabra
, Parth R Desai
, Johnathan Frunzi

HCA Florida Trinity Hospital

HCA Healthcare

Research output: Contribution to journal › Article › peer-review

Abstract

Adrenal crisis (AC) is a rare but known life-threatening condition in patients with adrenal insufficiency (AI). We report the case of a 21-year-old without known AI who developed AC after routine vaccinations. Workup revealed that the patient had underlying, undiagnosed autoimmune adrenalitis. This is the first report of AC induced by influenza and diphtheria, tetanus, and acellular pertussis (DTaP) vaccinations in a patient without known AI.

Original language	American English
Journal	Internal Medicine
State	Published - Jul 11 2021

Keywords

adrenal crisis
post-vaccination
autoimmune adrenalitis
primary adrenal insufficiency
seasonal influenza vaccine
tetanus vaccine

Disciplines

Endocrine System Diseases
Internal Medicine

Access to Document

https://doi.org/10.7759/cureus.16312

Cite this

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title = "Adrenal Crisis Secondary to Influenza and Tetanus Vaccination in an Adult Without Known Adrenal Insufficiency: A Case of Autoimmune Adrenalitis",

abstract = " Adrenal crisis (AC) is a rare but known life-threatening condition in patients with adrenal insufficiency (AI). We report the case of a 21-year-old without known AI who developed AC after routine vaccinations. Workup revealed that the patient had underlying, undiagnosed autoimmune adrenalitis. This is the first report of AC induced by influenza and diphtheria, tetanus, and acellular pertussis (DTaP) vaccinations in a patient without known AI.",

keywords = "adrenal crisis, post-vaccination, autoimmune adrenalitis, primary adrenal insufficiency, seasonal influenza vaccine, tetanus vaccine",

author = "Shiwani Kamath and Jessica Khabra and Desai, \{Parth R\} and Johnathan Frunzi",

note = "Kamath S, Khabra JK, Desai P, Frunzi J. Adrenal Crisis Secondary to Influenza and Tetanus Vaccination in an Adult Without Known Adrenal Insufficiency: A Case of Autoimmune Adrenalitis. Cureus. 2021;13(7):e16312. doi:10.7759/cureus.16312",

year = "2021",

month = jul,

day = "11",

language = "American English",

journal = "Internal Medicine",

}

TY - JOUR

T1 - Adrenal Crisis Secondary to Influenza and Tetanus Vaccination in an Adult Without Known Adrenal Insufficiency: A Case of Autoimmune Adrenalitis

AU - Kamath, Shiwani

AU - Khabra, Jessica

AU - Desai, Parth R

AU - Frunzi, Johnathan

N1 - Kamath S, Khabra JK, Desai P, Frunzi J. Adrenal Crisis Secondary to Influenza and Tetanus Vaccination in an Adult Without Known Adrenal Insufficiency: A Case of Autoimmune Adrenalitis. Cureus. 2021;13(7):e16312. doi:10.7759/cureus.16312

PY - 2021/7/11

Y1 - 2021/7/11

N2 - Adrenal crisis (AC) is a rare but known life-threatening condition in patients with adrenal insufficiency (AI). We report the case of a 21-year-old without known AI who developed AC after routine vaccinations. Workup revealed that the patient had underlying, undiagnosed autoimmune adrenalitis. This is the first report of AC induced by influenza and diphtheria, tetanus, and acellular pertussis (DTaP) vaccinations in a patient without known AI.

AB - Adrenal crisis (AC) is a rare but known life-threatening condition in patients with adrenal insufficiency (AI). We report the case of a 21-year-old without known AI who developed AC after routine vaccinations. Workup revealed that the patient had underlying, undiagnosed autoimmune adrenalitis. This is the first report of AC induced by influenza and diphtheria, tetanus, and acellular pertussis (DTaP) vaccinations in a patient without known AI.

KW - adrenal crisis

KW - post-vaccination

KW - autoimmune adrenalitis

KW - primary adrenal insufficiency

KW - seasonal influenza vaccine

KW - tetanus vaccine

UR - https://scholarlycommons.hcahealthcare.com/internal-medicine/207

UR - https://doi.org/10.7759/cureus.16312

M3 - Article

JO - Internal Medicine

JF - Internal Medicine

ER -

Adrenal Crisis Secondary to Influenza and Tetanus Vaccination in an Adult Without Known Adrenal Insufficiency: A Case of Autoimmune Adrenalitis

Abstract

Keywords

Disciplines

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