An Atypical Presentation of Neuroleptic Malignant Syndrome

Rudy Forte; Shiwani Kamath; Debra Angelo; Johnathan Frunzi

An Atypical Presentation of Neuroleptic Malignant Syndrome

Rudy Forte
, Shiwani Kamath
, Debra Angelo
, Johnathan Frunzi

HCA Florida Trinity Hospital

HCA Healthcare

Research output: Contribution to journal › Article › peer-review

Abstract

Neuroleptic Malignant Syndrome (NMS) is a rare, but potentially life threatening condition associated with dopamine blockade, particularly first-generation antipsychotics. The complex pathophysiology of NMS remains somewhat unclear and debatable as the symptoms are not fully explained by dopamine blockade alone. ¹ D2 dopamine receptor antagonism remains responsible for most cases of NMS, however a few cases have been reported in which little to no D2 blockade activity was present. ¹

This poster is about an atypical presentation of NMS.

Original language	American English
Journal	West Florida Division GME Research Day 2020
State	Published - May 1 2020

Keywords

Neuroleptic malignant syndrome; Atypical NMS; Aripiprazole induced NMS; Afebrile NMS

Disciplines

Internal Medicine
Nervous System Diseases
Psychiatry

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title = "An Atypical Presentation of Neuroleptic Malignant Syndrome",

abstract = " Neuroleptic Malignant Syndrome (NMS) is a rare, but potentially life threatening condition associated with dopamine blockade, particularly first-generation antipsychotics. The complex pathophysiology of NMS remains somewhat unclear and debatable as the symptoms are not fully explained by dopamine blockade alone. 1 D2 dopamine receptor antagonism remains responsible for most cases of NMS, however a few cases have been reported in which little to no D2 blockade activity was present. 1 This poster is about an atypical presentation of NMS.",

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author = "Rudy Forte and Shiwani Kamath and Debra Angelo and Johnathan Frunzi",

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AU - Kamath, Shiwani

AU - Angelo, Debra

AU - Frunzi, Johnathan

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Y1 - 2020/5/1

N2 - Neuroleptic Malignant Syndrome (NMS) is a rare, but potentially life threatening condition associated with dopamine blockade, particularly first-generation antipsychotics. The complex pathophysiology of NMS remains somewhat unclear and debatable as the symptoms are not fully explained by dopamine blockade alone. 1 D2 dopamine receptor antagonism remains responsible for most cases of NMS, however a few cases have been reported in which little to no D2 blockade activity was present. 1 This poster is about an atypical presentation of NMS.

AB - Neuroleptic Malignant Syndrome (NMS) is a rare, but potentially life threatening condition associated with dopamine blockade, particularly first-generation antipsychotics. The complex pathophysiology of NMS remains somewhat unclear and debatable as the symptoms are not fully explained by dopamine blockade alone. 1 D2 dopamine receptor antagonism remains responsible for most cases of NMS, however a few cases have been reported in which little to no D2 blockade activity was present. 1 This poster is about an atypical presentation of NMS.

KW - Neuroleptic malignant syndrome; Atypical NMS; Aripiprazole induced NMS; Afebrile NMS

UR - https://scholarlycommons.hcahealthcare.com/westflorida2020/1

M3 - Article

JO - West Florida Division GME Research Day 2020

JF - West Florida Division GME Research Day 2020

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An Atypical Presentation of Neuroleptic Malignant Syndrome

Abstract

Keywords

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