Anti-interleukin-21 antibody and liraglutide for the preservation of β-cell function in adults with recent-onset type 1 diabetes: a randomised, double-blind, placebo-controlled, phase 2 trial.

Matthias von Herrath; Stephen C Bain; Bruce Bode; Jesper Ole Clausen; Ken Coppieters; Leylya Gaysina; Janusz Gumprecht; Troels Krarup Hansen; Chantal Mathieu; Cristobal Morales; Ofri Mosenzon; Stine Segel; George Tsoukas; Thomas R Pieber; Bernhard Ludvik; Rudolf Prager; Bernhard Paulweber; Christoph F Ebenbichler; B Keymeulen; C De Block; Loren Grossman; Robyn Houlden; Patrice Perron; Thomas Ransom; Peter Senior; S. John Weisnagel; Vincent Woo; Richard Dumas; David Thompson; Tina Vilsbøll; Jeppe Gram; Claus Bogh Juhl; Janne Hukkanen; Jorma Lahtela; Leo Niskanen; Donal O'Shea; Timothy O'Brien; Seamus Sreenan; Julio Wainstein; Moshe Phillip; Hilla Knobler; Francesco Dotta; Pier Marco Piatti; Trevisan Roberto; Agostino Gnasso; Hanne Gulseth; John Cooper; Ewa Pankowska; Monika Lukaszewicz; Samer Nakhle

doi:10.1016/S2213-8587(21)00019-X

Anti-interleukin-21 antibody and liraglutide for the preservation of β-cell function in adults with recent-onset type 1 diabetes: a randomised, double-blind, placebo-controlled, phase 2 trial.

Matthias von Herrath
, Stephen C Bain
, Bruce Bode
, Jesper Ole Clausen
, Ken Coppieters
, Leylya Gaysina
, Janusz Gumprecht
, Troels Krarup Hansen
, Chantal Mathieu
, Cristobal Morales
, Ofri Mosenzon
, Stine Segel
, George Tsoukas
, Thomas R Pieber
, Bernhard Ludvik
, Rudolf Prager
, Bernhard Paulweber
, Christoph F Ebenbichler
, B Keymeulen
, C De Block

Loren Grossman, Robyn Houlden, Patrice Perron, Thomas Ransom, Peter Senior, S. John Weisnagel, Vincent Woo, Richard Dumas, David Thompson, Tina Vilsbøll, Jeppe Gram, Claus Bogh Juhl, Janne Hukkanen, Jorma Lahtela, Leo Niskanen, Donal O'Shea, Timothy O'Brien, Seamus Sreenan, Julio Wainstein, Moshe Phillip, Hilla Knobler, Francesco Dotta, Pier Marco Piatti, Trevisan Roberto, Agostino Gnasso, Hanne Gulseth, John Cooper, Ewa Pankowska, Monika Lukaszewicz, Samer Nakhle

Novo Nordisk
Swansea University
Emory University
Kazan Federal University
Medical University of Silesia
Aarhus University Hospital
Katholieke Universiteit Leuven
Hebrew University of Jerusalem
McGill University
Medical University of Graz

Research output: Contribution to journal › Article › peer-review

Original language	American English
Journal	The Lancet Diabetes & Endocrinology
Volume	9
Issue number	4
DOIs	https://doi.org/10.1016/S2213-8587(21)00019-X
State	Published - Apr 1 2021

Disciplines

Medicine and Health Sciences
Internal Medicine

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von Herrath, M., Bain, S. C., Bode, B., Clausen, J. O., Coppieters, K., Gaysina, L., Gumprecht, J., Hansen, T. K., Mathieu, C., Morales, C., Mosenzon, O., Segel, S., Tsoukas, G., Pieber, T. R., Ludvik, B., Prager, R., Paulweber, B., Ebenbichler, C. F., Keymeulen, B., ... Nakhle, S. (2021). Anti-interleukin-21 antibody and liraglutide for the preservation of β-cell function in adults with recent-onset type 1 diabetes: a randomised, double-blind, placebo-controlled, phase 2 trial. The Lancet Diabetes & Endocrinology, 9(4). https://doi.org/10.1016/S2213-8587(21)00019-X

Anti-interleukin-21 antibody and liraglutide for the preservation of β-cell function in adults with recent-onset type 1 diabetes: a randomised, double-blind, placebo-controlled, phase 2 trial. / von Herrath, Matthias; Bain, Stephen C; Bode, Bruce et al.
In: The Lancet Diabetes & Endocrinology, Vol. 9, No. 4, 01.04.2021.

Research output: Contribution to journal › Article › peer-review

von Herrath, M, Bain, SC, Bode, B, Clausen, JO, Coppieters, K, Gaysina, L, Gumprecht, J, Hansen, TK, Mathieu, C, Morales, C, Mosenzon, O, Segel, S, Tsoukas, G, Pieber, TR, Ludvik, B, Prager, R, Paulweber, B, Ebenbichler, CF, Keymeulen, B, De Block, C, Grossman, L, Houlden, R, Perron, P, Ransom, T, Senior, P, Weisnagel, SJ, Woo, V, Dumas, R, Thompson, D, Vilsbøll, T, Gram, J, Juhl, CB, Hukkanen, J, Lahtela, J, Niskanen, L, O'Shea, D, O'Brien, T, Sreenan, S, Wainstein, J, Phillip, M, Knobler, H, Dotta, F, Piatti, PM, Roberto, T, Gnasso, A, Gulseth, H, Cooper, J, Pankowska, E, Lukaszewicz, M & Nakhle, S 2021, 'Anti-interleukin-21 antibody and liraglutide for the preservation of β-cell function in adults with recent-onset type 1 diabetes: a randomised, double-blind, placebo-controlled, phase 2 trial.', The Lancet Diabetes & Endocrinology, vol. 9, no. 4. https://doi.org/10.1016/S2213-8587(21)00019-X

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AU - von Herrath, Matthias

AU - Bain, Stephen C

AU - Bode, Bruce

AU - Clausen, Jesper Ole

AU - Coppieters, Ken

AU - Gaysina, Leylya

AU - Gumprecht, Janusz

AU - Hansen, Troels Krarup

AU - Mathieu, Chantal

AU - Morales, Cristobal

AU - Mosenzon, Ofri

AU - Segel, Stine

AU - Tsoukas, George

AU - Pieber, Thomas R

AU - Ludvik, Bernhard

AU - Prager, Rudolf

AU - Paulweber, Bernhard

AU - Ebenbichler, Christoph F

AU - Keymeulen, B

AU - De Block, C

AU - Grossman, Loren

AU - Houlden, Robyn

AU - Perron, Patrice

AU - Ransom, Thomas

AU - Senior, Peter

AU - Weisnagel, S. John

AU - Woo, Vincent

AU - Dumas, Richard

AU - Thompson, David

AU - Vilsbøll, Tina

AU - Gram, Jeppe

AU - Juhl, Claus Bogh

AU - Hukkanen, Janne

AU - Lahtela, Jorma

AU - Niskanen, Leo

AU - O'Shea, Donal

AU - O'Brien, Timothy

AU - Sreenan, Seamus

AU - Wainstein, Julio

AU - Phillip, Moshe

AU - Knobler, Hilla

AU - Dotta, Francesco

AU - Piatti, Pier Marco

AU - Roberto, Trevisan

AU - Gnasso, Agostino

AU - Gulseth, Hanne

AU - Cooper, John

AU - Pankowska, Ewa

AU - Lukaszewicz, Monika

AU - Nakhle, Samer

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ER -

Anti-interleukin-21 antibody and liraglutide for the preservation of β-cell function in adults with recent-onset type 1 diabetes: a randomised, double-blind, placebo-controlled, phase 2 trial.

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