@article{9eb606ac905f405794bf6f1d937f38ed,
title = "Asymptomatic Blastomycosis of the Central Nervous System with Progression in Patients Given Ketoconazole Therapy: A Report of Two Cases",
author = "Yancey, \{Robert W.\} and Perlino, \{Carl A.\} and Leo Kaufman",
note = "Ketoconazole (KTZ) has largely replaced amphotericin B as first-line therapy for blastomycosis. However, KTZ penetrates poorly into the central nervous system (CNS), and therapeutic failure may be caused by initially unrecognized CNS infection. Two patients (22\% [2/9] of all culture-proven cases of blastomycosis at Grady Memorial Hospital, Atlanta, over 15 years) developed CNS blastomycosis while receiving KTZ.",
year = "1991",
month = oct,
day = "1",
doi = "10.1093/INFDIS/164.4.807",
language = "American English",
volume = "164",
journal = "The Journal of Infectious Diseases",
number = "4",
}