Control of plasma uric acid in adults at risk for tumor lysis syndrome: Efficacy and safety of rasburicase alone and rasburicase followed by allopurinol compared with allopurinol alone - Results of a multicenter phase III study

Jorge Cortes; Joseph O. Moore; Richard T. Maziarz; Meir Wetzler; Michael Craig; Jeffrey Matous; Selina Luger; Bimalangshu R. Dey; Gary J. Schiller; Dat Pham; Camille N. Abboud; Muthuswamy Krishnamurthy; Archie Brown; Abderrahmane Laadem; Karen Seiter

doi:10.1200/JCO.2009.26.8896

Control of plasma uric acid in adults at risk for tumor lysis syndrome: Efficacy and safety of rasburicase alone and rasburicase followed by allopurinol compared with allopurinol alone - Results of a multicenter phase III study

Jorge Cortes
, Joseph O. Moore
, Richard T. Maziarz
, Meir Wetzler
, Michael Craig
, Jeffrey Matous
, Selina Luger
, Bimalangshu R. Dey
, Gary J. Schiller
, Dat Pham
, Camille N. Abboud
, Muthuswamy Krishnamurthy
, Archie Brown
, Abderrahmane Laadem
, Karen Seiter

University of Texas MD Anderson Cancer Center

Research output: Contribution to journal › Article › peer-review

Original language	American English
Journal	Journal of Clinical Oncology
Volume	28
Issue number	27
DOIs	https://doi.org/10.1200/JCO.2009.26.8896
State	Published - Sep 20 2010

Disciplines

Medicine and Health Sciences
Gastroenterology
Surgery
Internal Medicine

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Cortes, J., Moore, J. O., Maziarz, R. T., Wetzler, M., Craig, M., Matous, J., Luger, S., Dey, B. R., Schiller, G. J., Pham, D., Abboud, C. N., Krishnamurthy, M., Brown, A., Laadem, A., & Seiter, K. (2010). Control of plasma uric acid in adults at risk for tumor lysis syndrome: Efficacy and safety of rasburicase alone and rasburicase followed by allopurinol compared with allopurinol alone - Results of a multicenter phase III study. Journal of Clinical Oncology, 28(27). https://doi.org/10.1200/JCO.2009.26.8896

Control of plasma uric acid in adults at risk for tumor lysis syndrome: Efficacy and safety of rasburicase alone and rasburicase followed by allopurinol compared with allopurinol alone - Results of a multicenter phase III study. / Cortes, Jorge; Moore, Joseph O.; Maziarz, Richard T. et al.
In: Journal of Clinical Oncology, Vol. 28, No. 27, 20.09.2010.

Research output: Contribution to journal › Article › peer-review

Cortes, J, Moore, JO, Maziarz, RT, Wetzler, M, Craig, M, Matous, J, Luger, S, Dey, BR, Schiller, GJ, Pham, D, Abboud, CN, Krishnamurthy, M, Brown, A, Laadem, A & Seiter, K 2010, 'Control of plasma uric acid in adults at risk for tumor lysis syndrome: Efficacy and safety of rasburicase alone and rasburicase followed by allopurinol compared with allopurinol alone - Results of a multicenter phase III study', Journal of Clinical Oncology, vol. 28, no. 27. https://doi.org/10.1200/JCO.2009.26.8896

Cortes J, Moore JO, Maziarz RT, Wetzler M, Craig M, Matous J et al. Control of plasma uric acid in adults at risk for tumor lysis syndrome: Efficacy and safety of rasburicase alone and rasburicase followed by allopurinol compared with allopurinol alone - Results of a multicenter phase III study. Journal of Clinical Oncology. 2010 Sep 20;28(27). doi: 10.1200/JCO.2009.26.8896

@article{c96ff65b26e1406199010817b874d380,

title = "Control of plasma uric acid in adults at risk for tumor lysis syndrome: Efficacy and safety of rasburicase alone and rasburicase followed by allopurinol compared with allopurinol alone - Results of a multicenter phase III study",

author = "Jorge Cortes and Moore, \{Joseph O.\} and Maziarz, \{Richard T.\} and Meir Wetzler and Michael Craig and Jeffrey Matous and Selina Luger and Dey, \{Bimalangshu R.\} and Schiller, \{Gary J.\} and Dat Pham and Abboud, \{Camille N.\} and Muthuswamy Krishnamurthy and Archie Brown and Abderrahmane Laadem and Karen Seiter",

note = "Purpose Rasburicase is effective in controlling plasma uric acid in pediatric patients with hematologic malignancies. This study in adults evaluated safety of and compared efficacy of rasburicase alone with rasburicase followed by oral allopurinol and with allopurinol alone in controlling plasma uric acid.",

year = "2010",

month = sep,

day = "20",

doi = "10.1200/JCO.2009.26.8896",

language = "American English",

volume = "28",

journal = "Journal of Clinical Oncology",

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T1 - Control of plasma uric acid in adults at risk for tumor lysis syndrome: Efficacy and safety of rasburicase alone and rasburicase followed by allopurinol compared with allopurinol alone - Results of a multicenter phase III study

AU - Cortes, Jorge

AU - Moore, Joseph O.

AU - Maziarz, Richard T.

AU - Wetzler, Meir

AU - Craig, Michael

AU - Matous, Jeffrey

AU - Luger, Selina

AU - Dey, Bimalangshu R.

AU - Schiller, Gary J.

AU - Pham, Dat

AU - Abboud, Camille N.

AU - Krishnamurthy, Muthuswamy

AU - Brown, Archie

AU - Laadem, Abderrahmane

AU - Seiter, Karen

N1 - Purpose Rasburicase is effective in controlling plasma uric acid in pediatric patients with hematologic malignancies. This study in adults evaluated safety of and compared efficacy of rasburicase alone with rasburicase followed by oral allopurinol and with allopurinol alone in controlling plasma uric acid.

PY - 2010/9/20

Y1 - 2010/9/20

UR - https://ascopubs.org/doi/10.1200/JCO.2009.26.8896

U2 - 10.1200/JCO.2009.26.8896

DO - 10.1200/JCO.2009.26.8896

M3 - Article

VL - 28

JO - Journal of Clinical Oncology

JF - Journal of Clinical Oncology

IS - 27

ER -

Control of plasma uric acid in adults at risk for tumor lysis syndrome: Efficacy and safety of rasburicase alone and rasburicase followed by allopurinol compared with allopurinol alone - Results of a multicenter phase III study

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