@article{3590d0a134bd43e5afc9fd33e42caecf,
title = "Ketamine-induced hepatoprotection: the role of heme oxygenase-1.",
author = "Suliburk, \{James W.\} and Ward, \{Jeremy L.\} and Helmer, \{Kenneth S.\} and Adams, \{Sasha D.\} and Zuckerbraun, \{Brian S.\} and Mercer, \{David W.\}",
note = "Lipopolysaccharide (LPS) causes hepatic injury that is mediated, in part, by upregulation of inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2). Ketamine has been shown to prevent these effects. Because upregulation of heme oxygenase-1 (HO-1) has hepatoprotective effects, as does carbon monoxide (CO), an end product of the HO-1 catalytic reaction, we examined the effects of HO-1 inhibition on ketamine-induced hepatoprotection and assessed whether CO could attenuate LPS-induced hepatic injury.",
year = "2009",
month = jun,
day = "1",
doi = "10.1152/AJPGI.00038.2009",
language = "American English",
volume = "296",
journal = "American Journal of Physiology-gastrointestinal and Liver Physiology",
issn = "1522-1547",
publisher = "American Physiological Society",
number = "6",
}