Low tidal volume and high positive end-expiratory pressure mechanical ventilation results in increased inflammation and ventilator-associated lung injury in normal lungs.

Caron M. Hong; Qi Lu; Yunhui Cheng; Vadim Pisarenko; Danielle Doucet; Margaret Brown; Seena Aisner; Chunxiang Zhang; Edwin A. Deitch; Ellise Delphin

doi:10.1213/ANE.0B013E3181CFC416

Low tidal volume and high positive end-expiratory pressure mechanical ventilation results in increased inflammation and ventilator-associated lung injury in normal lungs.

Caron M. Hong
, Qi Lu
, Yunhui Cheng
, Vadim Pisarenko
, Danielle Doucet
, Margaret Brown
, Seena Aisner
, Chunxiang Zhang
, Edwin A. Deitch
, Ellise Delphin

University of Medicine and Dentistry of New Jersey
Rutgers University

Research output: Contribution to journal › Article › peer-review

Original language	American English
Journal	Anesthesia & Analgesia
Volume	110
Issue number	6
DOIs	https://doi.org/10.1213/ANE.0B013E3181CFC416
State	Published - Jun 1 2010
Externally published	Yes

Disciplines

Medicine and Health Sciences
Anesthesiology

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Hong, C. M., Lu, Q., Cheng, Y., Pisarenko, V., Doucet, D., Brown, M., Aisner, S., Zhang, C., Deitch, E. A., & Delphin, E. (2010). Low tidal volume and high positive end-expiratory pressure mechanical ventilation results in increased inflammation and ventilator-associated lung injury in normal lungs. Anesthesia & Analgesia, 110(6). https://doi.org/10.1213/ANE.0B013E3181CFC416

Hong, CM, Lu, Q, Cheng, Y, Pisarenko, V, Doucet, D, Brown, M, Aisner, S, Zhang, C, Deitch, EA & Delphin, E 2010, 'Low tidal volume and high positive end-expiratory pressure mechanical ventilation results in increased inflammation and ventilator-associated lung injury in normal lungs.', Anesthesia & Analgesia, vol. 110, no. 6. https://doi.org/10.1213/ANE.0B013E3181CFC416

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title = "Low tidal volume and high positive end-expiratory pressure mechanical ventilation results in increased inflammation and ventilator-associated lung injury in normal lungs.",

author = "Hong, \{Caron M.\} and Qi Lu and Yunhui Cheng and Vadim Pisarenko and Danielle Doucet and Margaret Brown and Seena Aisner and Chunxiang Zhang and Deitch, \{Edwin A.\} and Ellise Delphin",

note = "BACKGROUND: Protective mechanical ventilation with low tidal volume (VT) and low plateau pressure reduces mortality and decreases the length of mechanical ventilation in patients with acute respiratory distress syndrome. Mechanical ventilation that will protect normal lungs during major surgical procedures of long duration may improve postoperative outcomes.",

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T1 - Low tidal volume and high positive end-expiratory pressure mechanical ventilation results in increased inflammation and ventilator-associated lung injury in normal lungs.

AU - Hong, Caron M.

AU - Lu, Qi

AU - Cheng, Yunhui

AU - Pisarenko, Vadim

AU - Doucet, Danielle

AU - Brown, Margaret

AU - Aisner, Seena

AU - Zhang, Chunxiang

AU - Deitch, Edwin A.

AU - Delphin, Ellise

N1 - BACKGROUND: Protective mechanical ventilation with low tidal volume (VT) and low plateau pressure reduces mortality and decreases the length of mechanical ventilation in patients with acute respiratory distress syndrome. Mechanical ventilation that will protect normal lungs during major surgical procedures of long duration may improve postoperative outcomes.

PY - 2010/6/1

Y1 - 2010/6/1

UR - https://einstein.pure.elsevier.com/en/publications/low-tidal-volume-and-high-positive-end-expiratory-pressure-mechan-2

U2 - 10.1213/ANE.0B013E3181CFC416

DO - 10.1213/ANE.0B013E3181CFC416

M3 - Article

SN - 1526-7598

VL - 110

JO - Anesthesia & Analgesia

JF - Anesthesia & Analgesia

IS - 6

ER -

Low tidal volume and high positive end-expiratory pressure mechanical ventilation results in increased inflammation and ventilator-associated lung injury in normal lungs.

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