@article{12d0725e055f4a29bfceed997db49529,
title = "Mathematical and statistical methods to model the trajectory and estimate the age at onset of Alzheimer's disease biomarker changes",
author = "Kewei Chen and Adam Fleisher and Napatkamon Ayutyanont and Yakeel Quiroz and Sergio Alvarez and Francisco Lopera and Eric Reiman",
note = "We have been using cross-sectional brain imaging, cerebrospinal fluid (CSF) and other measurements to characterize and compare the age-dependent trajectory of different Alzheimer's disease (AD) biomarker changes associated with the preclinical and clinical stages of AD in PS1 E280A mutation carriers and non-carriers from the world's largest early-onset AD kindred.",
year = "2012",
month = jul,
day = "1",
doi = "10.1016/J.JALZ.2012.05.170",
language = "American English",
volume = "8",
journal = "Alzheimers \& Dementia",
issn = "1552-5279",
publisher = "Elsevier",
number = "4",
}