MicroRNA-101 Inhibits Growth of Epithelial Ovarian Cancer by Relieving Chromatin-Mediated Transcriptional Repression of p21 waf1/cip1

Assaad Semaan; Aamer M. Qazi; Shelly Seward; Sreedhar Chamala; Christopher S. Bryant; Sanjeev Kumar; Robert Morris; Christopher P. Steffes; David L. Bouwman; Adnan R Munkarah; Donald W. Weaver; Scott A. Gruber; Ramesh B. Batchu

doi:10.1007/S11095-011-0547-X

MicroRNA-101 Inhibits Growth of Epithelial Ovarian Cancer by Relieving Chromatin-Mediated Transcriptional Repression of p21 waf1/cip1

Assaad Semaan
, Aamer M. Qazi
, Shelly Seward
, Sreedhar Chamala
, Christopher S. Bryant
, Sanjeev Kumar
, Robert Morris
, Christopher P. Steffes
, David L. Bouwman
, Adnan R Munkarah
, Donald W. Weaver
, Scott A. Gruber
, Ramesh B. Batchu

Wayne State University
University of Texas MD Anderson Cancer Center
Mayo Clinic
Henry Ford Health System
John D. Dingell VA Medical Center

Research output: Contribution to journal › Article › peer-review

Original language	American English
Journal	Pharmaceutical Research
Volume	28
Issue number	12
DOIs	https://doi.org/10.1007/S11095-011-0547-X
State	Published - Aug 5 2011
Externally published	Yes

Disciplines

Biology
Oncology

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Semaan, A., Qazi, A. M., Seward, S., Chamala, S., Bryant, C. S., Kumar, S., Morris, R., Steffes, C. P., Bouwman, D. L., Munkarah, A. R., Weaver, D. W., Gruber, S. A., & Batchu, R. B. (2011). MicroRNA-101 Inhibits Growth of Epithelial Ovarian Cancer by Relieving Chromatin-Mediated Transcriptional Repression of p21 waf1/cip1. Pharmaceutical Research, 28(12). https://doi.org/10.1007/S11095-011-0547-X

Semaan, A, Qazi, AM, Seward, S, Chamala, S, Bryant, CS, Kumar, S, Morris, R, Steffes, CP, Bouwman, DL, Munkarah, AR, Weaver, DW, Gruber, SA & Batchu, RB 2011, 'MicroRNA-101 Inhibits Growth of Epithelial Ovarian Cancer by Relieving Chromatin-Mediated Transcriptional Repression of p21 waf1/cip1', Pharmaceutical Research, vol. 28, no. 12. https://doi.org/10.1007/S11095-011-0547-X

@article{5ecdcab465014fb3bbf1ddbe042dc145,

title = "MicroRNA-101 Inhibits Growth of Epithelial Ovarian Cancer by Relieving Chromatin-Mediated Transcriptional Repression of p21 waf1/cip1",

author = "Assaad Semaan and Qazi, \{Aamer M.\} and Shelly Seward and Sreedhar Chamala and Bryant, \{Christopher S.\} and Sanjeev Kumar and Robert Morris and Steffes, \{Christopher P.\} and Bouwman, \{David L.\} and Munkarah, \{Adnan R\} and Weaver, \{Donald W.\} and Gruber, \{Scott A.\} and Batchu, \{Ramesh B.\}",

note = "Purpose MicroRNA-101 (miR-101) expression is negatively associated with tumor growth and proliferation in several solid epithelial cancers. Enhancer of zeste homolog 2 (EzH2) appears to be a functional target of miR-101. We explore the role of miR-101 and its interaction with EzH2 in epithelial ovarian carcinoma (EOC).",

year = "2011",

month = aug,

day = "5",

doi = "10.1007/S11095-011-0547-X",

language = "American English",

volume = "28",

journal = "Pharmaceutical Research",

number = "12",

}

TY - JOUR

T1 - MicroRNA-101 Inhibits Growth of Epithelial Ovarian Cancer by Relieving Chromatin-Mediated Transcriptional Repression of p21 waf1/cip1

AU - Semaan, Assaad

AU - Qazi, Aamer M.

AU - Seward, Shelly

AU - Chamala, Sreedhar

AU - Bryant, Christopher S.

AU - Kumar, Sanjeev

AU - Morris, Robert

AU - Steffes, Christopher P.

AU - Bouwman, David L.

AU - Munkarah, Adnan R

AU - Weaver, Donald W.

AU - Gruber, Scott A.

AU - Batchu, Ramesh B.

N1 - Purpose MicroRNA-101 (miR-101) expression is negatively associated with tumor growth and proliferation in several solid epithelial cancers. Enhancer of zeste homolog 2 (EzH2) appears to be a functional target of miR-101. We explore the role of miR-101 and its interaction with EzH2 in epithelial ovarian carcinoma (EOC).

PY - 2011/8/5

Y1 - 2011/8/5

UR - https://link.springer.com/article/10.1007/s11095-011-0547-x

U2 - 10.1007/S11095-011-0547-X

DO - 10.1007/S11095-011-0547-X

M3 - Article

VL - 28

JO - Pharmaceutical Research

JF - Pharmaceutical Research

IS - 12

ER -

MicroRNA-101 Inhibits Growth of Epithelial Ovarian Cancer by Relieving Chromatin-Mediated Transcriptional Repression of p21 waf1/cip1

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