Mutational analysis of EGFR signaling pathway genes in lung adenocarcinomas

J. L. Marks; M. D. McLellan; Y. Kasai; L. A. Fulton; E. R. Mardis; R. K. Wilson; M. F. Zakowski; V. W. Rusch; H. E. Varmus; W. Pao

doi:10.1200/JCO.2007.25.18_SUPPL.7584

Mutational analysis of EGFR signaling pathway genes in lung adenocarcinomas

J. L. Marks
, M. D. McLellan
, Y. Kasai
, L. A. Fulton
, E. R. Mardis
, R. K. Wilson
, M. F. Zakowski
, V. W. Rusch
, H. E. Varmus
, W. Pao

Research output: Contribution to journal › Article › peer-review

Original language	American English
Journal	Journal of Clinical Oncology
Volume	25
DOIs	https://doi.org/10.1200/JCO.2007.25.18_SUPPL.7584
State	Published - Jun 20 2007

Disciplines

Medicine and Health Sciences
Oncology

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10.1200/JCO.2007.25.18_SUPPL.7584License: Unspecified

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@article{4f971b5e22f74ec59a403c0d9c576c34,

title = "Mutational analysis of EGFR signaling pathway genes in lung adenocarcinomas",

author = "Marks, \{J. L.\} and McLellan, \{M. D.\} and Y. Kasai and Fulton, \{L. A.\} and Mardis, \{E. R.\} and Wilson, \{R. K.\} and Zakowski, \{M. F.\} and Rusch, \{V. W.\} and Varmus, \{H. E.\} and W. Pao",

note = "7584 Background: About fifty percent of lung adenocarcinomas harbor somatic mutations in six genes that encode signaling proteins in the EGFR signaling pathway, i.e. EGFR, HER2/ERBB2, HER4/ERBB4, PIK3CA, BRAF, and KRAS. We performed mutational profiling of a large cohort of lung adenocarcinomas to uncover other somatic mutations that could contribute to lung tumorigenesis.",

year = "2007",

month = jun,

day = "20",

doi = "10.1200/JCO.2007.25.18\_SUPPL.7584",

language = "American English",

volume = "25",

journal = "Journal of Clinical Oncology",

}

TY - JOUR

T1 - Mutational analysis of EGFR signaling pathway genes in lung adenocarcinomas

AU - Marks, J. L.

AU - McLellan, M. D.

AU - Kasai, Y.

AU - Fulton, L. A.

AU - Mardis, E. R.

AU - Wilson, R. K.

AU - Zakowski, M. F.

AU - Rusch, V. W.

AU - Varmus, H. E.

AU - Pao, W.

N1 - 7584 Background: About fifty percent of lung adenocarcinomas harbor somatic mutations in six genes that encode signaling proteins in the EGFR signaling pathway, i.e. EGFR, HER2/ERBB2, HER4/ERBB4, PIK3CA, BRAF, and KRAS. We performed mutational profiling of a large cohort of lung adenocarcinomas to uncover other somatic mutations that could contribute to lung tumorigenesis.

PY - 2007/6/20

Y1 - 2007/6/20

UR - https://ascopubs.org/doi/abs/10.1200/jco.2007.25.18_suppl.7584

U2 - 10.1200/JCO.2007.25.18_SUPPL.7584

DO - 10.1200/JCO.2007.25.18_SUPPL.7584

M3 - Article

VL - 25

JO - Journal of Clinical Oncology

JF - Journal of Clinical Oncology

ER -

Mutational analysis of EGFR signaling pathway genes in lung adenocarcinomas

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