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Outcome in recipients of dual kidney transplants: An analysis of the dual registry patients

  • Amy D. Lu
  • , Jonathan T. Carter
  • , Rebecca J. Weinstein
  • , Robert J. Stratta
  • , Rodney J. Taylor
  • , Victor D. Bowers
  • , Lloyd E. Ratner
  • , Kenneth D. Chavin
  • , Lynt B. Johnson
  • , Paul C. Kuo
  • , Edward H. Cole
  • , Donald C. Dafoe
  • , Edward J. Alfrey
  • Stanford University
  • University of Tennessee Health Science Center
  • University of Nebraska at Omaha
  • Lifelink Transplantation Institute
  • Johns Hopkins University
  • Georgetown University
  • University of Toronto

Research output: Contribution to journal › Article › peer-review

Abstract

Background. A novel but controversial method to increase the utilization of aged donor kidneys is the transplantation of both kidneys as a dual transplant. Initial single-center reports demonstrated outcomes similar to single kidneys from younger donors. In this report, we compare outcome in recipients of kidneys from donors ≥54 years of age who received a single kidney transplant reported to the United Network for Organ Sharing Scientific Registry versus a dual kidney transplant reported to the Dual Kidney Registry. Methods. A retrospective analysis was performed, comparing four donor and nine recipient and outcome variables between recipients of a single versus a dual transplant between March 1993 and March 1999. Results. Dual versus single transplants from donors ≥54 years of age have a significantly decreased incidence of delayed graft function, and lower serum creatinines up to 2 years after transplant despite having kidneys from significantly older donors with poorer HLA matching. Conclusions. Dual kidney transplants improve graft performance and outcome in recipients of kidneys from donors ≥54 years of age.

Original languageAmerican English
JournalTransplantation
Volume69
Issue number2
DOIs
StatePublished - Jan 27 2000
Externally publishedYes

Disciplines

  • Medicine and Health Sciences
  • Surgery
  • Internal Medicine

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