@article{4aa0295ab3a54a31a5e4eecba782e523,
title = "Pyruvate mitigates oxidative stress during reperfusion of cardioplegia-arrested myocardium.",
author = "Knott, \{E. Marty\} and Jie Sun and Yu Lei and Myoung-Gwi Ryou and Olivencia-Yurvati, \{Albert H.\} and Mallet, \{Robert T.\}",
note = "Background. Cardioplegic arrest and reperfusion of the myocardium imposes oxidative stress that could potentially inactivate metabolic enzymes and compromise energy production. This study determined the impact of cardioplegic arrest and reperfusion on activities of several oxidant-sensitive enzymes, and tested whether pyruvate, a natural metabolic fuel and antioxidant, mitigates oxidant stress, protects enzymes, and bolsters myocardial energy state after reperfusion.",
year = "2006",
month = mar,
day = "1",
doi = "10.1016/J.ATHORACSUR.2005.08.046",
language = "American English",
volume = "81",
journal = "The Annals of Thoracic Surgery",
number = "3",
}