Rare Complication of a Commonly Used Antihypertensive Agent: A Case of Hydralazine-Induced ANCA-Associated Vasculitis Presenting as Rapidly Progressive Glomerulonephritis

Kayle M Warren; Khiem T Vu; Karandeep Shergill; Brian Watson; Mohamed Faris

Rare Complication of a Commonly Used Antihypertensive Agent: A Case of Hydralazine-Induced ANCA-Associated Vasculitis Presenting as Rapidly Progressive Glomerulonephritis

Kayle M Warren
, Khiem T Vu
, Karandeep Shergill
, Brian Watson
, Mohamed Faris

Grand Strand Medical Center

HCA Healthcare

Research output: Contribution to journal › Article › peer-review

Abstract

Hydralazine-induced ANCA-associated vasculitis is a rare clinical entity, with complications including rapidly progressive glomerulonephritis, pulmonary hemorrhage, and pulmonary-renal syndrome. We present this case to highlight the clinical features that support this challenging diagnosis and to emphasize the importance of prompt recognition and aggressive intervention given its significant morbidity and mortality.

Original language	American English
Journal	Internal Medicine
State	Published - Feb 7 2022

Keywords

drug‐induced vasculitis
hydralazine
pulmonary hemorrhage
pulmonary‐renal syndrome
rapidly progressive glomerulonephritis

Disciplines

Cardiovascular Diseases
Internal Medicine

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https://doi.org/10.1002/ccr3.5411

Cite this

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title = "Rare Complication of a Commonly Used Antihypertensive Agent: A Case of Hydralazine-Induced ANCA-Associated Vasculitis Presenting as Rapidly Progressive Glomerulonephritis",

abstract = " Hydralazine-induced ANCA-associated vasculitis is a rare clinical entity, with complications including rapidly progressive glomerulonephritis, pulmonary hemorrhage, and pulmonary-renal syndrome. We present this case to highlight the clinical features that support this challenging diagnosis and to emphasize the importance of prompt recognition and aggressive intervention given its significant morbidity and mortality.",

keywords = "drug‐induced vasculitis, hydralazine, pulmonary hemorrhage, pulmonary‐renal syndrome, rapidly progressive glomerulonephritis",

author = "Warren, \{Kayle M\} and Vu, \{Khiem T\} and Karandeep Shergill and Brian Watson and Mohamed Faris",

note = "Warren K, Vu K, Shergill K, Watson B, Faris M. Rare complication of a commonly used antihypertensive agent: A case of hydralazine-induced ANCA-associated vasculitis presenting as rapidly progressive glomerulonephritis. Clin Case Rep. 2022;10(2):e05411. Published 2022 Feb 7. doi:10.1002/ccr3.5411",

year = "2022",

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day = "7",

language = "American English",

journal = "Internal Medicine",

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T1 - Rare Complication of a Commonly Used Antihypertensive Agent: A Case of Hydralazine-Induced ANCA-Associated Vasculitis Presenting as Rapidly Progressive Glomerulonephritis

AU - Warren, Kayle M

AU - Vu, Khiem T

AU - Shergill, Karandeep

AU - Watson, Brian

AU - Faris, Mohamed

N1 - Warren K, Vu K, Shergill K, Watson B, Faris M. Rare complication of a commonly used antihypertensive agent: A case of hydralazine-induced ANCA-associated vasculitis presenting as rapidly progressive glomerulonephritis. Clin Case Rep. 2022;10(2):e05411. Published 2022 Feb 7. doi:10.1002/ccr3.5411

PY - 2022/2/7

Y1 - 2022/2/7

N2 - Hydralazine-induced ANCA-associated vasculitis is a rare clinical entity, with complications including rapidly progressive glomerulonephritis, pulmonary hemorrhage, and pulmonary-renal syndrome. We present this case to highlight the clinical features that support this challenging diagnosis and to emphasize the importance of prompt recognition and aggressive intervention given its significant morbidity and mortality.

AB - Hydralazine-induced ANCA-associated vasculitis is a rare clinical entity, with complications including rapidly progressive glomerulonephritis, pulmonary hemorrhage, and pulmonary-renal syndrome. We present this case to highlight the clinical features that support this challenging diagnosis and to emphasize the importance of prompt recognition and aggressive intervention given its significant morbidity and mortality.

KW - drug‐induced vasculitis

KW - hydralazine

KW - pulmonary hemorrhage

KW - pulmonary‐renal syndrome

KW - rapidly progressive glomerulonephritis

UR - https://scholarlycommons.hcahealthcare.com/internal-medicine/299

UR - https://doi.org/10.1002/ccr3.5411

M3 - Article

JO - Internal Medicine

JF - Internal Medicine

ER -

Rare Complication of a Commonly Used Antihypertensive Agent: A Case of Hydralazine-Induced ANCA-Associated Vasculitis Presenting as Rapidly Progressive Glomerulonephritis

Abstract

Keywords

Disciplines

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