Renal cortical necrosis following a colonoscopy

Rajeev Raghavan

doi:10.5414/CN107171

Renal cortical necrosis following a colonoscopy

Rajeev Raghavan

HCA Houston Healthcare Kingwood

Research output: Contribution to journal › Article › peer-review

Abstract

A 76-year old African-American male presented with profound renal failure within 2 weeks after a screening colonoscopy. Polyethylene glycol (PEG) was the sole oral preparatory agent. The significantly elevated lactate dehydrogenase (LDH) and biopsy findings were consistent with acute renal cortical necrosis (RCN). PEG is associated with AKI, but the exact mechanism is uncertain. PEG can be biodegraded to diethylene glycol (DEG), which is a nephrotoxic agent associated with RCN. Three months after presentation, the patient remains hemodialysis dependent.

Original language	American English
Journal	Clinical Nephrology
Volume	79
Issue number	1
DOIs	https://doi.org/10.5414/CN107171
State	Published - Jan 2013

Disciplines

Medicine and Health Sciences
Nephrology

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10.5414/CN107171License: Unspecified

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title = "Renal cortical necrosis following a colonoscopy",

abstract = " A 76-year old African-American male presented with profound renal failure within 2 weeks after a screening colonoscopy. Polyethylene glycol (PEG) was the sole oral preparatory agent. The significantly elevated lactate dehydrogenase (LDH) and biopsy findings were consistent with acute renal cortical necrosis (RCN). PEG is associated with AKI, but the exact mechanism is uncertain. PEG can be biodegraded to diethylene glycol (DEG), which is a nephrotoxic agent associated with RCN. Three months after presentation, the patient remains hemodialysis dependent. ",

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AB - A 76-year old African-American male presented with profound renal failure within 2 weeks after a screening colonoscopy. Polyethylene glycol (PEG) was the sole oral preparatory agent. The significantly elevated lactate dehydrogenase (LDH) and biopsy findings were consistent with acute renal cortical necrosis (RCN). PEG is associated with AKI, but the exact mechanism is uncertain. PEG can be biodegraded to diethylene glycol (DEG), which is a nephrotoxic agent associated with RCN. Three months after presentation, the patient remains hemodialysis dependent.

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Renal cortical necrosis following a colonoscopy

Abstract

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