@article{2004766725624f4eb4aac1d3d35b6ed5,
title = "Resuscitation of the injured patient with polymerized stroma-free hemoglobin does not produce systemic or pulmonary hypertension",
author = "Johnson, \{Jeffrey L\} and Moore, \{Ernest E\} and Offner, \{Patrick J\} and Haenel, \{James B\} and Hides, \{George A\} and Tamura, \{Douglas Y\}",
note = "Background: Hemoglobin-based blood substitutes appear poised to deliver the promise of a universally compatible, disease-free alternative to banked blood. However, vasoconstriction following administration of tetrameric hemoglobins has been problematic, likely because of nitric oxide binding. Polymerized hemoglobin is effectively excluded from the abluminal space because of its size, and is thus less likely to perturb vasorelaxation.",
year = "1998",
month = dec,
day = "1",
doi = "10.1016/S0002-9610(98)00275-X",
language = "American English",
volume = "176",
journal = "American Journal of Surgery",
issn = "1879-1883",
number = "6",
}