@article{ba8240d526c14e4db5746a9dea5b3fc4,
title = "Silencing megalin and cubilin genes inhibits myeloma light chain endocytosis and ameliorates toxicity in human renal proximal tubule epithelial cells.",
author = "Min Li and Saravanan Balamuthusamy and Simon, \{Eric E.\} and Vecihi Batuman",
note = "immunoglobulin light chains (LCs) are normally filtered relatively unhindered in the glomerulus, are endocytosed in proximal tubule cells, and enter the endosomal-lysosomal path for catabolism ( 1). We previously demonstrated that LC endocytosis in renal proximal tubule cells is a receptor-mediated process ( 2, 3, 11) and that the recently characterized multiligand endocytic receptor system megalin/cubilin plays a key role in this process ( 6, 16, 20, 28).",
year = "2008",
month = jul,
day = "1",
doi = "10.1152/AJPRENAL.00091.2008",
language = "American English",
volume = "295",
journal = "American Journal of Physiology-renal Physiology",
number = "1",
}