Spitting Blood and Casts with Mud: A Rare and Unusual Presentation of C3 Glomerulonephritis

Gerardo Mederos; Harsh Patel; Menalee Hapuarachchi; Som Aftabizadeh; Prashanth Reddy; Ranjit Nair; Dana Ciobanu; Machaiah Madhrira

Spitting Blood and Casts with Mud: A Rare and Unusual Presentation of C3 Glomerulonephritis

Gerardo Mederos
, Harsh Patel
, Menalee Hapuarachchi
, Som Aftabizadeh
, Prashanth Reddy
, Ranjit Nair
, Dana Ciobanu
, Machaiah Madhrira

Medical City Fort Worth

HCA Healthcare

Research output: Contribution to journal › Article › peer-review

Abstract

C3 glomerulonephritis (C3GN) is a rare disease that falls under the umbrella of C3 glomerulopathy. It is manifested by abnormal activation of the alternate pathway resulting in complement deposition in the glomeruli. Kidney biopsy with characteristic findings of electron-dense deposits in the mesangial and capillary wall confirms the diagnosis. Until recently, C3GN presenting with primarily lung involvement had not been reported. We present a unique case of initial pulmonary manifestation C3GN.

Original language	American English
Journal	Internal Medicine
State	Published - Oct 25 2019

Keywords

kidney disease
glomeruli
pulmonary renal syndrome
PRS

Disciplines

Internal Medicine
Male Urogenital Diseases
Nephrology

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Spitting Blood and Casts with Mud A Rare and Unusual PresentatioFinal published version, 89.9 KBLicense: Unspecified

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title = "Spitting Blood and Casts with Mud: A Rare and Unusual Presentation of C3 Glomerulonephritis",

abstract = " C3 glomerulonephritis (C3GN) is a rare disease that falls under the umbrella of C3 glomerulopathy. It is manifested by abnormal activation of the alternate pathway resulting in complement deposition in the glomeruli. Kidney biopsy with characteristic findings of electron-dense deposits in the mesangial and capillary wall confirms the diagnosis. Until recently, C3GN presenting with primarily lung involvement had not been reported. We present a unique case of initial pulmonary manifestation C3GN.",

keywords = "kidney disease, glomeruli, pulmonary renal syndrome, PRS",

author = "Gerardo Mederos and Harsh Patel and Menalee Hapuarachchi and Som Aftabizadeh and Prashanth Reddy and Ranjit Nair and Dana Ciobanu and Machaiah Madhrira",

note = "Mederos G, et al. Spitting Blood and Casts with Mud: A Rare and Unusual Presentation of C3 Glomerulonephritis. Poster presented at: Texas ACP Annual Meeting; October 25-27, 2019; San Antonio, TX.",

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journal = "Internal Medicine",

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T1 - Spitting Blood and Casts with Mud: A Rare and Unusual Presentation of C3 Glomerulonephritis

AU - Mederos, Gerardo

AU - Patel, Harsh

AU - Hapuarachchi, Menalee

AU - Aftabizadeh, Som

AU - Reddy, Prashanth

AU - Nair, Ranjit

AU - Ciobanu, Dana

AU - Madhrira, Machaiah

N1 - Mederos G, et al. Spitting Blood and Casts with Mud: A Rare and Unusual Presentation of C3 Glomerulonephritis. Poster presented at: Texas ACP Annual Meeting; October 25-27, 2019; San Antonio, TX.

PY - 2019/10/25

Y1 - 2019/10/25

N2 - C3 glomerulonephritis (C3GN) is a rare disease that falls under the umbrella of C3 glomerulopathy. It is manifested by abnormal activation of the alternate pathway resulting in complement deposition in the glomeruli. Kidney biopsy with characteristic findings of electron-dense deposits in the mesangial and capillary wall confirms the diagnosis. Until recently, C3GN presenting with primarily lung involvement had not been reported. We present a unique case of initial pulmonary manifestation C3GN.

AB - C3 glomerulonephritis (C3GN) is a rare disease that falls under the umbrella of C3 glomerulopathy. It is manifested by abnormal activation of the alternate pathway resulting in complement deposition in the glomeruli. Kidney biopsy with characteristic findings of electron-dense deposits in the mesangial and capillary wall confirms the diagnosis. Until recently, C3GN presenting with primarily lung involvement had not been reported. We present a unique case of initial pulmonary manifestation C3GN.

KW - kidney disease

KW - glomeruli

KW - pulmonary renal syndrome

KW - PRS

UR - https://scholarlycommons.hcahealthcare.com/internal-medicine/41

M3 - Article

JO - Internal Medicine

JF - Internal Medicine

ER -

Spitting Blood and Casts with Mud: A Rare and Unusual Presentation of C3 Glomerulonephritis

Abstract

Keywords

Disciplines

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