@article{7560e6fe10b24302a122c59a98972200,
title = "The Alzheimer{\textquoteright}s Prevention Initiative composite cognitive test score: Sample size estimates for the evaluation of preclinical Alzheimer{\textquoteright}s disease treatments in presenilin 1 E280A mutation carriers",
author = "Napatkamon Ayutyanont and Langbaum, \{Jessica B S\} and Hendrix, \{Suzanne B\} and Kewei Chen and Fleisher, \{Adam S\} and Michel Friesenhahn and Michael Ward and Camilo Aguirre and Natalia Acosta-Baena and Luc{\`i}a Madrigal and Claudia Mu{\~n}oz and Victoria Tirado and Sonia Moreno and Tariot, \{Pierre N\} and Francisco Lopera and Reiman, \{Eric M\}",
note = "Method: We capitalized on longitudinal data collected from 1995 to 2010 from cognitively unimpaired presenilin 1 (PSEN1) E280A mutation carriers from the world's largest known early-onset autosomal dominant Alzheimer's disease kindred to identify a composite cognitive test with the greatest statistical power to track preclinical Alzheimer's disease decline and estimate the number of carriers age 30 years and older needed to detect a treatment effect in the Alzheimer's Prevention Initiative's (API) preclinical Alzheimer's disease treatment trial.",
year = "2014",
month = apr,
day = "15",
doi = "10.4088/JCP.13M08927",
language = "American English",
volume = "75",
journal = "The Journal of Clinical Psychiatry",
number = "6",
}