Vein in Vain: A Case of Deep Vein Thrombosis Following the Use of the Mynx Closure Device

Vascular closure devices (VCDs) have significantly advanced catheter-based interventions by expediting hemostasis following arterial puncture. The Mynx closure device, which uses a sealant consisting of polyethylene glycol (PEG) to facilitate hemostasis, is a widely used tool for arterial closure. Despite their effectiveness, these devices are still associated with complications, including thrombosis and vessel occlusion, which warrant attention. We report a case involving a 58-year-old male with a complex medical history, including atrial flutter and nonischemic cardiomyopathy, who presented with right lower extremity pain following catheter ablation for atrial flutter. Hemostasis was effectively achieved by using the Mynx closure device. Despite successful recovery, the patient developed a DVT within the right lower extremity, involving the femoral and iliac veins which necessitated mechanical thrombectomy. While VCDs such as the Mynx closure device have shown superior benefits in reducing hemostasis time and improving patient comfort, instances of complications such as deep vein thrombosis and vessel occlusion have been reported. The potential for such complications suggests a need for proper training and careful monitoring to minimize risks.